Fatiguing Leaky Integrate and Fire Neurons

• Another problem is that if you get a neuron to fire at a high rate with a constant current, it tends to slow down.
• I call this fatigue, but most folks call it adaptation.
• It's usually modeled with an extra variable in the point equations.
• That variable, which I'll call fatigue, increases when a neuron fires,
• and decreases when a neuron doesn't fire.
• The fatigue value is used to increase the firing threshold. When a neuron has fired a lot, it needs more activation to fire.
• I've also used it to generate spontaneous firing.
• (If you take an in vitro neuron that has no inputs, most will spike quite regularly about once a second.)
• So, if the neuron becomes hypo-fatigued, it spikes.