Coding Structural Plasticity

• If you want to change this in PyNN and Nest, you can simulate for a while, then add new synapses or neurons, then simulate for a bit longer.
• If you want to remove synapses or neurons, you have to get rid of the entire old set between steps.
• Alternatively, if the synapses are static, you can set the weights to 0.
• This is a PyNN Nest limitation. Other systems, like the SpiNNaker neuromorphic system, can dynamically change topologies.
• There's no theoretical difficulty.